Endocrine Abstracts

Serum CT is the most specific marker of Medullary Thyroid carcinoma (MTC). Although Pg test is the most frequently used to induce CT secretion, the poor availability of Pg makes it necessary to look for different agents. Aim of this work was to compare the induction of CT secretion following 2 different stimuli in the same patient. We studied 25 patients (14 females, 11 males; mean age 50±15 yrs; range 12–77 yrs). All patients were subjected to both tests by injectio...

Up to now there isn’t any study to validate the CT measurement in wash-out-fluid from FNAB in the diagnosis of medullary thyroid cancer (MTC). To demonstrate the usefulness of CT measurement in wash-out fluid from FNAB in thyroid nodules, we have retrospectively analyzed 25 cases with detectable serum CT in which CT measurement in wash-out-fluid from FNAB, citology and histological examination were available. In 7 cases CT level was <10 pg/ml: cytology was negative in...

BRAFV600E is the most common mutation in papillary thyroid carcinoma (PTC). Anatomo-patology and clinical features of PTC with BRAFV600E are well described in literature.Aim of this study was to examine the prognostic significance of BRAFV600E in patients with PTC and a follow-up of 15-20 years.Genomic DNA was purified from 67 paraffin-embedded tumoral tissue. A PCR-SSCP analysis of exon 15 of BRAF ...